For the people who live along a coast (almost anywhere), it is a source of food and commerce, dotted with ports of entry for travellers of whatever stripe.
We would do well to remember that these routes exist to move people from place to place, not to please our aesthetic sensibilities and *every* route will have its industrial sections at some point. Some routes have less (but only if we remove farming from the equation, and I'm not sure that's an accurate subtraction).
Nothing wrong with leaving the coastal route and heading inland. I did it because I am from a coast and so the ocean isn't really *new* to me (much as I love it). I adored the central route but it too has industry (strip mines for granite, wineries, general commercial transport...).
It helps to remember that we are in a region where the land and water uses are determined by those who live there and that our wants are secondary to their needs.